p

g

p p

e the gene is a bimodal gene.

The example of bimodal gene with outliers. The triangles are outliers. The dots

y greater circles stand for the boundary by which expressions are separated into

ulations.

gure 6.38, the gene contains two replicates with extremely low

ns. They are treated as the outliers with the same reason. After

g these two outliers, the rest expressions show a well-structured

distribution as shown as the inset histogram in the plot.

e, this gene may not be treated as a bimodal gene.

An example of potentially misclassified bimodal gene with outlier expressions.

and for expressions of a gene and the dots enclosed by the triangles are outliers.

e 6.39 shows how the bimodal index test may have a problem for

ta set. Using the letrozole drug breast cancer treatment data for

nstration, the bimodal index test predicted 9,230 bimodal genes.